Hamilton researchers have figured out why women are less likely to get Type 2 diabetes than men, and it's a discovery that has led them to a "new target" when it comes to developing treatment options.
In identifying a pathway and protein that "jams" the signal between insulin and muscles, which leads to Type 2 diabetes, researchers found women are more efficient at processing the protein PTEN, leading to a greater protection from developing diabetes.
That protein, and pathway, finally explains why women are less likely to develop Type 2 diabetes, said Dr. M. Constantine Samaan, the lead author of the study, assistant professor of pediatrics at the Michael G. DeGroote School of Medicine and pediatric endocrinologist at the McMaster Children’s Hospital.
"This protein is a potential target that we can try and manipulate as a treatment and prevention strategy for insulin resistance in Type 2 diabetes," Samaan said of the study, published this week in the journal Scientific Reports.
Read more at the source article : http://bit.ly/1ExmWaT, site : http://www.cbc.ca
In identifying a pathway and protein that "jams" the signal between insulin and muscles, which leads to Type 2 diabetes, researchers found women are more efficient at processing the protein PTEN, leading to a greater protection from developing diabetes.
That protein, and pathway, finally explains why women are less likely to develop Type 2 diabetes, said Dr. M. Constantine Samaan, the lead author of the study, assistant professor of pediatrics at the Michael G. DeGroote School of Medicine and pediatric endocrinologist at the McMaster Children’s Hospital.
"This protein is a potential target that we can try and manipulate as a treatment and prevention strategy for insulin resistance in Type 2 diabetes," Samaan said of the study, published this week in the journal Scientific Reports.
Read more at the source article : http://bit.ly/1ExmWaT, site : http://www.cbc.ca
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